Salivary caffeine concentrations are comparable to plasma concentrations in preterm infants receiving extended caffeine therapy

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Salivary caffeine concentrations are comparable to plasma concentrations in preterm infants receiving extended caffeine therapy.

AIMS Caffeine concentrations in preterm infants are usually measured in the blood. However, salivary assays may provide a valid and practical alternative. The present study explored the validity and clinical utility of salivary caffeine concentrations as an alternative to blood concentrations and developed a novel plasma/salivary caffeine distribution model. METHODS Paired salivary and plasma...

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The objective of this study was to measure the umbilical cord plasma levels of cocaine, nicotine, caffeine, and their metabolites. Thirty-six neonates at risk for prenatal cocaine exposure were prospectively enrolled. Umbilical cord plasma was analyzed by gas chromatography-mass spectroscopy for cocaine, cocaethylene, benzoylecgonine (BZE), nicotine, cotinine, and caffeine. Eighteen neonates we...

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Plasma 25-hydroxyvitamin D concentrations in preterm infants receiving oral vitamin D supplements.

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ژورنال

عنوان ژورنال: British Journal of Clinical Pharmacology

سال: 2016

ISSN: 0306-5251,1365-2125

DOI: 10.1111/bcp.13001